Brain Metastases from Breast Cancers


  • Brief epidemiology and anatomy of CNS metastases 
  • Challenges in CNS directed medicine
  • A sample of recent breast cancer brain mets clinical trials:
    • Novel agents: her2CLIMB study in her2+ metastatic breast cancer and ANG1005 in breast LMD
    • Novel Administration: Intrathecal trastuzumab and high-dose trastuzumab in breast cancer
  • Ongoing/Emerging Clinical Trials and Future Directions



Course summary
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Priya Kumthekar, MD

Northwestern University


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